I'm in agreement with "the other Jeff"...I'm also in the same boat, getting set to open up my own shop after years of playing pizzeria at home. I have the business management experience, have the people management experience, and think there is a market in my small town for that non-chain type of place. I'd recommend getting your base pizza down, down well...and build from that. I think it's going to serve me well when I open to have my focus be the star, having so many "specialties" on my menu in the end might just mean there's nothing "special" about any of them? I'll open with my base pizza, the regular midwest toppings, 5 sandwiches, 3 salads, and maybe 3 pasta choices. But, I also plan to start adding in "limited time specials" after I get my kitchen humming. I know I'll run a "taco" pizza for a while, and some of the other great ideas I'm gleaning off this, and other, boards. Then, IF they take root, great. I'll have a built in following for them, but I'll already have built that customer base from day one with my main game.
Just my random thoughts, and like someone else points out..."your mileage may vary"!

Jeff